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PRP Therapy in Charlotte, NC

PRP Therapy for Low Back Pain in Charlotte, NC

Non-surgical PRP injections placed under live X-ray for facet arthritis, degenerative disc disease, sciatica, SI joint dysfunction and spinal stenosis, performed by NeoGenix's board-certified physicians in Charlotte.

Low back conditions we treat
Facet arthritisDisc degenerationSciaticaSI joint painSpinal stenosis

Why patients choose NeoGenix

6,000+ ProceduresRegenerative medicine procedures performed, the most in the Carolinas
250+ 5-Star ReviewsFrom patients across the Carolinas
1 Treatment ONLYWith our high-dose SuperShot® PRP
Little to No DowntimeNO steroids, medications, or surgery

The Low Back PRP Therapy Process

  • Source: Autologous (from you)
  • Low Back Conditions We Treat: Facet arthritis, degenerative disc disease, sciatica, SI joint dysfunction, and spinal stenosis
  • Stage of Arthritis or Injury: Mild to less moderate

Platelet-rich plasma (PRP) is among the fastest-growing areas in regenerative medicine. It utilizes the body's own healing components to boost tissue healing. PRP therapy uses a large number of autologous platelets in the patient's plasma. The platelets are injected into or directly applied to the tissue.

A Non-Surgical Solution for Low Back Pain

Low Back PRP From a Clinic That Only Does Regenerative Medicine

PRP (Platelet-Rich Plasma) or SuperShot® PRP treatment is an effective option when low back pain comes from mild to moderate injury or degeneration of the discs, joints, muscles, tendons, and other connective tissues of the lumbosacral spine. More moderate to severe conditions may require bone marrow treatment instead.

Regenerative medicine is all NeoGenix does; we do not offer PRP as a side service to another specialty. Before any treatment, a NeoGenix doctor examines you and reviews your imaging and medical history to confirm you are a good candidate, and every lumbar spine treatment is performed under live X-ray guidance by a board-certified doctor.

Conditions We Treat

What Causes of Low Back Pain Can PRP Help?

Facet Arthritis

The wearing down of the protective cartilage in the small joints of the lower back, leading to stiffness, inflammation, and lower back pain.

Degenerative Disc Disease

The natural wear and tear of the shock-absorbing cushions between your spine's bones, which can cause local or radiating pain.

Sciatica

Pain, tingling, or numbness that radiates from your lower back and buttock down one of your legs, caused by compression or irritation of the sciatic nerve.

Radiculopathy

A pinched or irritated nerve root in the lower back that causes pain, numbness, or weakness radiating down the leg.

SI Joint Dysfunction

Pain in the lower back, buttocks, and pelvis when the joint connecting the spine and pelvis moves too much or too little.

Piriformis Syndrome

Occurs when the piriformis muscle in the buttock spasms or tightens and puts pressure on the sciatic nerve, causing a deep, aching, or sharp pain in the middle of the buttock.

Ligament Strains

Happens when the tough bands of tissue holding the lower back vertebrae together are overstretched or torn, causing localized pain, stiffness, and decreased range of motion.

Spinal Stenosis

The narrowing of the spinal canal in the lower back that can compress the nerves traveling to the legs, causing pain, numbness or tingling in the buttocks and legs.

More Than One Spot

Where Is PRP Injected into the Lower Back?

Unlike a cortisone injection or an epidural into your lumbar spine, which can only target one small area because of the harmful side effects of the steroid, PRP can be injected into multiple areas at the same time.

Even if L4/L5 is your only issue based on your MRI or X-ray, we typically still inject PRP into your facet joints on both sides, all the way from L3 down to S1. We also inject your SI joints and any other muscles, tendons, and ligaments that we feel will help relieve your low back pain. By blanketing your entire lumbar spine with PRP, we get your whole low back functioning better, which takes the pressure off the discs and other areas that are causing your pain.

NeoGenix physician performing a spinal injection under live X-ray (fluoroscopy)
Delivered precisely to the site of injury.
Fluoroscopy Guided

Why Live X-Ray Guidance Is Essential in the Spine

All low back PRP injections are performed with fluoroscopic guidance (live X-ray) by our board-certified medical doctors to ensure the platelets are delivered safely to the exact area of injury. The spine is where precise placement matters most, because of the small size of the facet joints, the unique, irregular angle of the SI joints, and the risks of injecting the wrong area. Spinal injections done without fluoroscopic guidance are not only a serious safety risk; it is essentially impossible to accurately inject these areas without live X-ray.

Live X-ray, every spinal injectionPlatelets land in the exact joint, not near it.
Small, angled targetsThe facet joints are small and the SI joints sit at an irregular angle.
Board-certified medical doctorsEvery low back injection is performed by a NeoGenix physician.
Blood Draw to Injection

How the PRP Procedure Works

Step1

The Blood Draw

Professor Bansal's groundbreaking study demonstrated that a targeted dose of approximately 10 billion platelets in 8 mL of PRP is critical for achieving long-term clinical efficacy. A minimum of 120 mL of blood must be drawn to achieve the proper platelet counts. If that is not happening, you are not receiving high-dose PRP. Our nurse will draw your blood, then you will wait approximately 45 minutes for your PRP to be prepared.

Be sure to drink plenty of water the day of your PRP procedure to make the blood draw go more smoothly.

Step2

The Centrifuge

This is the second critical step to creating high-dose PRP. Higher dosing leads to better results. We believe in utilizing cutting-edge innovation to produce the best results for our patients. To create our high-dose PRP, our inventors created a desktop version of what blood banks and the American Red Cross use, and nobody knows how to generate high platelet counts for patients in need better than they do. Our nurses spend about 45 minutes processing your platelets by hand in between each spin in the centrifuge machine. You can be assured that the quality, safety, and effectiveness of our treatments are second to none. We are very proud of that.

High-dose PRP being prepared at NeoGenix

Our PRP centrifuge system produces a much higher level of platelets than Orthopedic and Physical Medicine and Rehabilitation (PM&R) clinics using easy-to-operate centrifuge machines that anyone can run by just pressing a button. The major flaw of these machines is that they are not capable of separating unwanted red blood cells when they are programmed to produce a higher platelet count. Too many red blood cells in a PRP injection is not outright toxic, but "red cell contamination" can increase post-injection pain and inflammation while lowering the treatment's overall effectiveness.

Step3

The NeoGenix Difference: Adding Autologous Exosomes to PRP = SuperShot® PRP

Most legitimate centrifuge machines require 2 spins: the first to separate the red blood cells and the second to separate the platelets from the plasma. After the second spin, most clinics simply throw that plasma away. Not at NeoGenix. We add the SuperShot® PRP solution to the remaining plasma and spin it in the centrifuge machine a 3rd time. In doing so, we are adding hundreds of billions of exosomes to your PRP. Exosomes are tiny messenger particles released by cells to help reduce joint inflammation and signal damaged low back tissues to repair themselves. In head-to-head lab testing with leading off-the-shelf exosome donor tissue products, SuperShot® PRP was shown to have 166 times more exosomes (see lab results).

The SuperShot PRP process: a triple-spin process that adds exosomes and A2M for a more complete platelet-rich plasma

A 2-year study comparing SuperShot® PRP to regular PRP showed that SuperShot® PRP created significantly better patient outcomes with longer-lasting results (see the study).

After Your Injection

Recovery and What to Expect

Day 1Most SoreThe night of the injection and the next day are when your low back will feel it most.
Days 2 to 4Soreness FadesSoreness eases off. No real restrictions, so get up, walk and trust your body.
Week 1Back to BaselineYour 1-week follow-up should find your back right where it was before treatment.
Weeks 3 to 6Results BeginResults usually start showing as the platelets slowly heal the joints and soft tissue of your lumbar spine.
Start PT
1 to 2 weeks after

Start a physical therapy or rehab program 1 to 2 weeks after your injection. PRP works on your low back joints, muscles, tendons, and ligaments internally. If you have muscle weakness or compensation issues around your low back, a rehab professional needs to correct them to maximize your results.

Treating the right low back conditions with PRP, we expect years of long-lasting relief.

PRP or Stem Cell Therapy

When Does Low Back Pain Require Stem Cell Therapy Instead of PRP?

PRP is an excellent treatment option for mild to less moderate low back conditions. It is important to remember that PRP does not contain stem cells, only growth factors. For patients with moderate to severe low back pain, arthritis, and radicular symptoms, we recommend stem cell therapy to treat your low back to help heal damaged cartilage and tissue.

As long as your low back pain is not causing severe weakness in your legs or other concerning neurological symptoms, stem cell therapy may be able to prevent you from having low back surgery.

Compare Your Options

PRP vs. Cortisone and Epidurals

In the traditional medical model, cortisone and epidural injections are commonly the first options offered by spine doctors or PM&R pain doctors.

Cortisone and Epidurals

Cortisone shots have been well studied. They can provide some short-term relief by turning off your pain receptors and helping with inflammation. They are only masking the pain and are doing nothing to actually heal your injury. Long-term, repeated use of cortisone is shown to damage your joints, muscles, tendons and ligaments over time (see study).

PRP Therapy

Nowadays, almost every spine doctor or PM&R doctor offers some version of PRP. Unlike cortisone and epidurals, PRP can actually heal and repair the damaged cartilage and tissue in your low back.

Studies now show that PRP is safer and provides much better long-term results when compared to cortisone or epidural injections into your lumbar spine (see study).

FeaturePRP TherapyCortisone and Epidural Injections
Cost to PatientLow to moderateLow
Cost to InsuranceNoneLow
Tissue RegenerationYesNo
Natural HealingYesNo
Recovery TimeLess than a week1 to 2 days
Start to See Improvement3 to 6 weeksWithin a week
Duration of ImprovementPotentially yearsWeeks to months
Complications and RisksHighly unlikelyCauses joint degeneration
James Altizer, M.D., NeoGenix
James Altizer, M.D.Owner and Director of Regenerative Medicine, NeoGenix
A Note From Dr. Altizer

David's Sciatica Went From a 7 to a 2 in 6 Weeks

After already successfully treating David's knee with PRP in early 2025, he came back to see me to treat his low back in August of 2025. He had mild to moderate low back pain and constant 7/10 sciatica pain that had lingered for the last few months. This time I did SuperShot® PRP into his bilateral L3-S1 facet joints and both of his SI joints. It only took him about 6 weeks for his pain to be reduced to 2/10, and now, over a year later, his back and sciatica are still doing great.

Dr. AltizerJames Altizer, M.D.

Individual results may vary.

FREE Consultation

Find Out If Low Back PRP Is Right for You

Bring your MRI or X-rays if you have them. A NeoGenix doctor will examine your back, review your history, and tell you honestly whether PRP, SuperShot® PRP or stem cell therapy is the right fit.

Charlotte

16147 Lancaster Hwy #140
Charlotte, NC 28277

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Lake Norman

19475 Old Jetton Rd #102
Cornelius, NC 28031

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Mon to Thu 9am to 5pm · Fri 9am to 12pm

Questions

Low Back PRP FAQs

Does low back PRP work for a herniated disc?
Yes. We typically inject PRP into the facet joints on both sides from L3 to S1, the SI joints on both sides, and any other muscles, tendons or ligaments we deem necessary. By helping the entire lumbar spine function and move better, it takes the pressure off the disc. Most stem cell experts do not inject directly into the disc, as studies have been inconclusive on whether puncturing the disc is the right course of action versus injecting around it.
Should I get low back PRP or an epidural steroid injection?
PRP. An epidural or cortisone shot can quiet back pain for a while, but it only masks it. PRP works to heal and repair the damaged cartilage and tissue in your lumbar spine, which makes it the safer, longer-lasting option. Studies have also shown that repeated cortisone injections harm joints, muscles, tendons, and ligaments.
Is it normal for my back to hurt more at first?
Yes, that is normal. Soreness usually lasts 2 to 4 days and peaks the night of the injection and the following day. Once it eases, there are no real restrictions: keep moving and trust your body. At your 1-week follow-up, we expect you to be back to baseline.
How many low back treatments will I need?
With our high-dose PRP and SuperShot® PRP injections, the platelet and exosome counts are so high you will typically only require 1 injection to resolve your pain and improve your function in your low back. While PRP is incredibly successful for mild to less moderate conditions, it rarely provides long-lasting results for moderate to severe conditions. Many clinics will stack 3 to 4 PRP injections together over the course of 4 to 6 months to treat moderate to severe conditions; we don't. If your low back condition warrants more powerful treatment, the answer is not multiple PRP injections; the answer is stem cell therapy.
How long does low back PRP last?
At NeoGenix, we use the highest dosing of platelets possible for our regular PRP and add billions of exosomes and A2M healing properties to our SuperShot® PRP. Because our PRP is so strong, we expect you to have years of long-lasting relief.
Does insurance cover spinal PRP?
Insurance does not cover PRP. However, many of the supportive therapies recommended alongside a PRP injection, such as physical therapy, are covered by insurance. For a cost breakdown of PRP, please see our PRP pricing guide.
What is the success rate of low back PRP?
Our board-certified medical doctors have treated over 6,000 patients with regenerative medicine, with an average 94%* success rate (how we measure success). Part of the reason our success rate is so high is that we only offer PRP if your condition warrants it. More complex low back issues are typically resolved more successfully with stem cell therapy instead of PRP.

Request Your FREE Consultation

Thank you for your interest in NeoGenix. For more information, or to schedule a FREE consultation, please call or text us at 704-727-6551 or simply fill out the form below and a NeoGenix team member will respond as soon as possible.